Use of 5-fluorocytosine in patients with impaired renal function.
نویسندگان
چکیده
The plasma level and elimination of 5-fluorocytosine (5-FC) was measured in normal subjects and patients with impaired renal function. Prolongation of the half-life of the drug in renal failure has been confirmed. Renal clearance of 5-FC was about 75% of the creatinine clearance and a corresponding modification of drug dosage should be made in patients with renal insufficiency.
منابع مشابه
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ورودعنوان ژورنال:
- British medical journal
دوره 4 5889 شماره
صفحات -
تاریخ انتشار 1973